Preclinical Spinal Muscular Atrophy (SMA) Studies
With a wealth of experience in preclinical spinal muscular atrophy (SMA) studies, PsychoGenics is an ideal choice to partner with...
Preclinical Duchenne Muscular Dystrophy (DMD) Studies
At PsychoGenics, we provide transformative solutions for preclinical DMD research, driving rigorous scientific inquiry into this X-linked genetic disorder marked...
Preclinical Charcot-Marie-Tooth (CMT) Disease Studies
PsychoGenics, in collaboration with the Charcot-Marie-Tooth Association (CMTA), is at the forefront of this research, devoted to the exploration and...
Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex
Lena H.Nguyen, Steven C.Leiser, Dekun Song, Daniela Brunner, Steven L.Roberds, Michael Wong, Angelique Bordey Tuberous sclerosis complex (TSC) is a...
Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex
Theilmann, W,Gericke,B,Schidlitzki, A, Anjum, S,Borsdorf, S, Harries, T, Roberds, S.L., Aguiar, D,Brunner, D, Leiser, S,Song, D, Fabbro, D,Hillmann, P, Wymann,...
Differences in Synaptic Dysfunction Between rTg4510 and APP/PS1 Mouse Models of Alzheimer’s Disease
Gelman S, Palma J, Tombaugh G, Ghavami A Journal of Alzheimer’s Disease, vol. 61, no. 1, pp. 195-208, 2018 DOI:...
Immunohistochemistry (IHC) & Histology Services
PsychoGenics’ immunohistochemistry (IHC) and histology services offer exceptional data quality, enabling the exploration of standard and novel biomarkers. Our high-throughput...
Preclinical Autism Spectrum Disorder (ASD) Studies
Approximately 2% of individuals with autism carry detrimental mutations in the SHANK3 gene, which plays a crucial role in organizing...