Resources
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington’s disease: zQ175
Menalled L, Kudwa A, Miller S, Fitzpatrick J, Watson-Johnson J, Keating N, Ruiz M, Mushlin R, Alosio B, McConnell K,...
Resources
Effect of the rd1 mutation on motor performance in R6/2 and wild type mice. PLoS Currents Huntington Disease.
Menalled, L., El-Khodor, B. F., Hornberger, M., Park, L., Howland, D., and Brunner, D.
Resources
Caspase-6 activity in a BAC HD mouse modulates steady state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.
Juliette Gafni, Theodora Papanikolaou, Francesco DeGiacomo, Jennifer Holcomb, Sylvia Chen, Menalled L.; Kudwa A.; Jon Fitzpatrick, Miller S.; Ramboz S.;...
Resources
HD mouse models reveal clear deficits in learning to perform a simple instrumental response. PLoS Currents: Huntington Disease.
Oakeshott, S., Port, R. G., Cummins-Sutphen, J., Watson-Johnson, J., Ramboz, S., Park, L., Howland, D., and Brunner, D.
Resources
Comprehensive behavioral testing in the R6/2 mouse model of Huntington’s disease shows no benefit from CoQ10 or minocycline.
Menalled, L. B.; Patry, M.; Ragland, N.; Lowden, P. A.; Goodman, J.; Minnich, J.; Zahasky, B.; Park, L.; Leeds, J.;...