Bassem F. El-Khodor, Karma James, Qing Chang, Wei Zhang, Yvette R. Loiselle, Chinmayee Panda & Taleen Hanania Nutritional Neuroscience, DOI: 10.1080/1028415X.2021.1995119, https://doi.org/10.1080/1028415X.2021.1995119
Objectives: Inadequate dietary magnesium (Mg) intake is a growing public health concern. Mg is critical for diverse metabolic processes including energy production, macromolecule biosynthesis, and electrolyte homeostasis. Inadequate free Mg2+ ion concentration ([Mg2+]) in the brain is associated with several neurological and behavioral disorders. Elevating [Mg2+]in the brain using oral Mg supplementation has proven to be challenging due to the tight regulation of Mg2+ transport to the brain. This stu[pdfjs-viewer url=”https%3A%2F%2Fwww.psychogenics.com%2Fwp-content%2Fuploads%2F2021%2F11%2FElevation-of-brain-magnesium-with-Swiss-chard-and-buckwheat-extracts-in-an-animal-model-of-reduced-magnesium-dietary-intake.pdf” viewer_width=100% viewer_height=800px fullscreen=true download=true print=true]dy explored the effect of short-term moderate reduction in dietary Mg intake (87% of normal Mg diet for 30 days) on [Mg2+] in the cerebrospinal fluid (CSF) ([Mg2+]CSF) and red blood cells (RBCs) ([Mg2+]RBC) in adult male rats. In addition, we investigated the effectiveness of magnesium-rich blend of Swiss chard and buckwheat extracts (SC/BW extract) in increasing brain [Mg2+] compared to various Mg salts commonly used as dietary supplements.