PrePulse Inhibition (PPI) of Acoustic Startle

The acoustic startle reflex is a very basic response to strong exteroceptive stimuli. A weak sound preceding the loud acoustic stimulus inhibits the startle reflex; this is called pre-pulse inhibition. It is widely used to assess sensorimotor reactivity (gating) in animals and humans, which is impaired in schizophrenia.

PrePulse Inhibition PrePulse Inhibition

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