S. RAMBOZ, A. PENNINGTON, K. COX, M. HALL, W. ARIAS, K. KAYSER, J. GUTERL, M. BANSAL, D. HAVAS, K. CIRILLO Parkinson’s disease (PD) and synucleinophathies are neurodegenerative disorders defined by α-synuclein (α-syn) accumulation. Mutations in the α-syn gene have...
W. J. XU, A. EDWARDS, K. COX, K. CIRILLO, J. A. AVILA, S. RAMBOZ Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neuronal loss in the substantia nigra with accumulation of α synuclein containing Lewy bodies. A number of rodent...
T. HEIKKINEN, T. BRAGGE, S. KOPONEN, T. PARKKARI, G. TOMBAUGH, S. GELMAN, S. ZHONG, L. DEVI, A. GHAVAMI, K. CIRILLO, A. BARRE, F. GACKIERE, D. GUIMOND, S. ZAPETTINI, B. SAVA, P. CHAUSSON, E. STEIDL, B. BUISSON, K. KUHLBRODT, A. KAKOULIDOU, S. JOBUSCH, K. TILLACK, A....
L. K. CUDDY, D. PROKOPENKO, R. BRIMBERRY, E. CUNNINGHAM, P. SONG, D. PROCISSI, T. HANANIA, S. C. LEISER, R. E. TANZI, R. J. VASSAR The angiotensin I converting enzyme (ACE1) gene (ACE) has been recently established as a genome-wide significant Alzheimer’s disease (AD)...
N. DEDIC1, P. G. JONES1, S. C. HOPKINS1, R. LEW1, T. HANANIA2, U. C. CAMPBELL1, K. S. KOBLAN1 1Sunovion Pharmaceuticals Inc., Marlborough, MA; 2Psychogenics Inc., Paramus, NJ. For the past 50 years, the clinical efficacy of antipsychotic medications has relied on...
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