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Teamwork, Excellence, Creativity and Entrepreneurial Spirit

At PsychoGenics we value teamwork, excellence, creativity and entrepreneurial drive. We are excited about our mission and endeavor each day to build a company that fosters that excitement. We believe that our employees are our most important and valued asset and we are committed to the creation of a working environment that encourages each employee’s professional and personal development. We believe in rewarding the efforts of our employees through competitive compensation and a comprehensive benefits plan.

Job Openings

Principal Scientist / Senior Principal Scientist Medicinal Chemistry, Drug Discovery

About PsychoGenics

PsychoGenics is a well-established preclinical Contract Research Organization (CRO) that provides comprehensive preclinical testing capabilities in CNS and orphan disorders. PsychoGenics has established several automated behavioral platforms, including the SmartCube® platform that provide phenotypic screening at an industrial level to support drug discovery programs. The Company is establishing a drug discovery group to exploit their technology platforms and is seeking to hire medicinal chemists at the Principal Scientist/Senior Principal Scientist level. The appointees will report to the Vice President of Medicinal Chemistry.

Overview of Position:

The successful applicants will be accomplished medicinal chemists, with a proven track record, and who can develop and lead drug discovery projects at PsychoGenics, with a focus on developing new small-molecule therapies for CNS disorders. Candidates will be expected to have strong technical and problem-solving skills in medicinal chemistry with expertise in the use of computational drug design to aid drug discovery. Proven experience of successful “hands on” chemistry in the laboratory, managing chemistry outsourcing, and a deep understanding of pharmacokinetic and drug metabolism studies, biology and pharmacology, will be expected. With good interpersonal skills, the successful applicants will take a leading role in interactions with collaborators, both within existing projects and in developing new research programs. Exceptional written and oral communication skills, interpersonal skills and critical thinking skills will be required.

Key Responsibilities:

  • Act as chemistry project leader for PsychoGenics CNS projects with the goal to identify novel pre-clinical candidates
  • Through both “hands on” laboratory chemistry and the use of external vendors (CRO’s), identify hit compounds and optimize them for in vitro, in vivo and toxicological properties
  • Use computationally assisted drug design (CADD) techniques to guide lead optimization studies
  • Interact closely with key collaborators both internally and externally including biologists, pharmacologists, drug discovery and development organizations and develop and manage relationships with collaborators and partners
  • Contribute to the dissemination of research results in the form of presentations at internal drug discovery meetings and external meetings
  • Assist the VP with the management of additional PsychoGenics research programs, initiatives and projects
  • Assist in growing the newly established drug discovery group at PsychoGenics

Qualifications:

  • Ph.D. in chemistry or medicinal chemistry with 5-10 years or more postdoctoral experience in biotech or the pharmaceutical industry with a focus on small molecule drug discovery
  • Proven track record of medicinal chemistry and drug discovery to identify pre-clinical candidates and documented in the form of publications
  • Familiar with the use of phenotypic screening in drug discovery
  • Creative and scientifically-oriented and who continually keeps up to date with the literature to keep abreast of new methods and techniques
  • Excellent verbal and written communication and interpersonal skills
  • Demonstrated ability to work effectively within a team and with external partners

To apply for the position please send your resume to Rebecca Buonadies



Senior Biologist, Drug Discovery

A highly motivated biologist with extensive experience leading drug discovery and development efforts for CNS programs through close collaboration with others.

Key Responsibilities:

  • Provide biological strategy and strong scientific, technical, and organizational leadership to drive drug discovery and development efforts supporting selected CNS projects
  • Oversee biological study designs and execution, data analysis and report writing
  • Participate in a multi-disciplinary team of biologists and chemists to progress programs
  • Stay abreast of the latest scientific and competitive developments and apply knowledge to project strategy
  • Prepare and present hypotheses, on-going progress reports, technical reports and future planning (including contributing to budgets and business plans)
  • Contribute to building a culture that embraces scientific excellence and integrity with a sense of urgency and collaboration with key stakeholders
  • Assume project responsibilities and effectively present updates to the senior leadership team

Qualifications:

  • Ph.D. in biochemistry, cell biology, pharmacology or a related scientific field
  • 5+ years of experience in CNS drug discovery in a pharmaceutical and/or biotech environment
  • Experience working with cross-functional teams
  • Familiarity with the preclinical regulatory requirements for small molecule development
  • Excellent communication skills with the proven ability to work effectively as a member of a multidisciplinary team
  • Excellent interpersonal skills and the desire to succeed in a collaborative work environment

To apply for the position please send your resume to Rebecca Buonadies



Research Associate 1 - Behavioral Pharmacology

We are looking for a highly motivated Research Associate in behavioral neuroscience. The successful candidate will work in a team of scientists and researchers supporting the preclinical studies using rodent models and tests. The primary responsibilities of the candidate will include but are not limited to conducting preclinical research of drug abuse liability, pain, cognition, and other assays as needed. The candidate must be capable of working across teams and independently.

Key Responsibilities:

  • Execution of rodent studies in behavioral pharmacology pain assays
  • Preliminary experimental data analysis

Qualifications:

  • A Bachelors degree in life sciences, neuroscience, or psychology with 1+ years of laboratory and behavioral experience with rats and/or mice
  • Experience with a variety of behavioral tests with rats and mice, including operant conditioning based experiments preferred
  • Able to work well in a group atmosphere as well as independently
  • Good organization and troubleshooting skills
  • High level of commitment, excellent motivation to perform and to learn
  • Able to comprehend and comply with all SOP and IACUC, safety and quality assurance protocols
  • Computer skills on Microsoft Office and statistical software

To apply for the position please send your resume to Rebecca Buonadies



Research Associate – Immunohistochemistry

Key Responsibilities:

  • Conduct laboratory projects from embedding to sectioning, labeling to imaging
  • Conduct laboratory projects in different departments
  • Work with samples which will be of animal and human origin
  • Embed, prepare and analyze biological tissue samples
  • Tissue cutting
  • Do histochemical stainings, immunohistochemistry
  • Do imaging and image analysis
  • Work with standard histological equipment such as cryostats; microtomes, microscopes and digital slide scanner
  • Place laboratory orders

Qualifications:

  • Bachelor’s degree in Biological Sciences required
  • 2 + years’ experience in IHC and Histology
  • Demonstrated skills including paraffin and/or cryo cutting, handling chemicals, lab math and preparation of solution and dilutions, immuno-histochemical protocols and microscopy
  • Excellent communication skills, organizational skills, and attention to detail

To apply for the position please send your resume to Rebecca Buonadies



Animal Care Technician

Key Responsibilities:

  • Review, comprehend, and comply with all SOPs, IACUC policies, safety, and quality assurance standards related to assigned work area.
  • Daily husbandry of the rodents in the vivarium to include the provision of feed, water, clean cages, and enrichment.
  • Basic sanitation and maintenance of colony rooms to include sweeping and mopping of animal quarters, rotating animal cages, racks and room supplies for cleaning according to schedule, disinfecting all areas in room.
  • Monitor the health of the animals and report any sick or dead to the PVC and room lab contact staff.
  • Receive and house shipments of animals.
  • Bedding sample collection for sentinels; assist with sentinel program procedures as needed.
  • Maintain accurate documentation records as required; including room logs.
  • Monitor room conditions including temperature, humidity, room and rack airflow, and lighting; with timely reporting of any issues to facilities.
  • Maintain adequate PPE, PVC kit, and other common room supplies by monitoring levels, and restocking as required.
  • Monitoring of animal health, and perform procedures such as teeth trims, antibiotic treatments, animal handling, euthanasia, and other simple procedures as certified trained and as required.
  • Ensure availability to work on weekends and holidays as required.
  • Regularly lift up to 50 pounds and move heavy equipment in a safe manner, and have the ability to stand, bend, reach, or crouch while working.

Qualifications:

  • Ability to regularly lift up to 50 pounds and move heavy equipment in a safe manner.
  • Ability to regularly stand, bend, reach, or crouch while working.
  • Strong communication skills interacting with vivarium management and research staff.
  • Availability to work on weekends and holidays as required to maintain compliance in animal care and use, providing oversight of animals 24/7.
  • High school diploma or GED required.
  • Experience in a laboratory animal facility strongly preferred.
  • Achieve ALAT certification after 1 year of employment.

To apply for the position please send your resume to Rebecca Buonadies



Senior Research Associate - Behavioral Pharmacology

We are looking for a highly motivated Senior Research Associate in behavioral neuroscience. The successful candidate will work in a team of scientists and researchers supporting the preclinical studies using rodent models and tests. The primary responsibilities of the candidate will include, but are not limited to conducting preclinical research of drug abuse liability, pain, cognition, and other assays as needed. The candidate will be responsible for surgeries, proper execution of experiments and preliminary data analysis. The candidate must be capable of working across teams and independently.

Key Responsibilities:

  • Execution of rodent studies in behavioral pharmacology, including drug abuse liability studies (such as intravenous self-administration and drug discrimination)
  • Executions of rodent surgeries in relevant studies (especially jugular vein catheter surgery in rats)
  • Preliminary experimental data analysis and draft of study report

Qualifications:

  • A Bachelors or Masters degree in life sciences, neuroscience, or psychology with 5+ years of laboratory and behavioral experience with rats and/or mice
  • Experience with a variety of behavioral tests with rats and mice, including operant conditioning based experiments
  • Surgical skills and dosing experience (IP, SC, PO, etc.)
  • Knowledge of pain assays desirable
  • Able to work well in a group atmosphere as well as independently
  • Good organization and troubleshooting skills
  • High level of commitment, excellent motivation to perform and to learn
  • Able to comprehend and comply with all SOP and IACUC, safety and quality assurance protocols
  • Computer skills on Microsoft Office and statistical software

To apply for the position please send your resume to Rebecca Buonadies



Research Associate 2/ Research Associate 3 - Behavioral Pharmacology

We are looking for a highly motivated Research Associate in behavioral neuroscience. The successful candidate will work in a team of scientists and researchers supporting the preclinical studies using rodent models and tests. The primary responsibilities of the candidate will include but are not limited to conducting preclinical research of drug abuse liability, pain, cognition, and other assays as needed. The candidate will be responsible for surgeries, proper execution of experiments and preliminary data analysis. The candidate must be capable of working across teams and independently.

Key Responsibilities:

  • Execution of rodent studies in behavioral pharmacology pain assays preferred
  • Executions of rodent surgeries in relevant studies (jugular vein catheter surgery in rats a plus)
  • Preliminary experimental data analysis and draft of study report

Qualifications:

  • A Bachelors or Masters degree in life sciences, neuroscience, or psychology with 2+ years of laboratory and behavioral experience with rats and/or mice
  • Experience with a variety of behavioral tests with rats and mice, including operant conditioning based experiments
  • Surgical skills and dosing experience (IP, SC, PO, etc.)
  • Knowledge of pain assays desirable
  • Able to work well in a group atmosphere as well as independently
  • Good organization and troubleshooting skills
  • High level of commitment, excellent motivation to perform and to learn
  • Able to comprehend and comply with all SOP and IACUC, safety and quality assurance protocols
  • Computer skills on Microsoft Office and statistical software

To apply for the position please send your resume to Rebecca Buonadies



Research Associate/ Senior Research Associate - Neurodegeneration Group

Key Responsibilities:

  • Primary tasks performed on a daily basis in mice will include Test Article dosing (IP, SC, IV, PO) using various routes of administration, behavioral testing, tissue collection (anatomical dissection of brain region, along with peripheral organs and muscles) and data handling (graphing and analyzing data).
  • Stereotaxic surgical techniques in rodents would be a plus, but not required.
  • Strong organizational and multitasking skills required.
  • Understanding of and compliance with company SOP’s and IACUC guidelines as well as safety and quality assurance standards related to the assigned work.
  • Follow proper protocol and safety procedures, as well as question and/or report any deviations to study protocols.

Qualifications include:

  • Bachelors or Master’s degree in the biological sciences, neuroscience, or related field.
  • Minimum three years of experience in handling and dosing of rodents in a laboratory setting.
  • Organizational, multi-tasking, trouble shooting and deductive reasoning skills required, along with a willingness and ability to work both independently and as part of a team.
  • Must be willing to work in a dynamic fast-paced environment.
  • Working knowledge of Microsoft Windows, Word, Excel and PowerPoint.
  • Occasional weekend and holiday work will be required.

To apply for the position please send your resume to Rebecca Buonadies







 

Career Opportunities

  • PsychoGenics
  • 215 College Road, Paramus, NJ 07652
  • Tel: (914) 406-8000
  • Fax: (914) 406-8090