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| Tail Suspension |
| Services - Depression - Tail Suspension |
| When mice are suspended by their tails, they become motionless which, as with the forced swim test, is thought to reflect a depressive-like state. This immobility is reduced by a large variety of clinically active antidepressants of different subclasses. | |
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| Antidepressants, Desipramine, Buproprion, and Fluoxetine all have a significant decrease in the time immobile in the tail suspension test in A/J Mice |
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| Triple and double re-uptake inhibitors DOV-21947 and Venlafaxine decrease immobility in the Tail Suspension test in 129SVEV mice. |
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