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Phenotyping & BreedingResearchers studying new drug targets need comprehensive ways to assess a target's relevance to CNS disorders. Use of knockout and transgenic mice with careful phenotyping has proven to be a powerful method, with the potential not only to validate hypotheses about gene function but also to uncover unexpected functions. PsychoGenics has developed a systematic series of behavioral tests known as PsychoScreen™ that measures a broad range of behavioral and neurological modalities (such as anxiety, mood, cognition, neuromotor function, pain, sleep, and attention) to help investigators phenotype their transgenic mice. Researchers who choose to run PsychoScreen™ or a modified version thereof instead of more limited studies can avoid missing valuable information or unexpected side effects of targets.
PsychoScreen™ can uncover potential signs of anxiety, depression, schizophrenia, eating disorders, cognitive disorders and dementia, mania, epilepsy, pain, addiction, ADHD and impulsivity, neuromotor disorders, sleep disorders, and sexual disorders. More then a dozen tests are run, and the results indicate how strongly the behavior relates to each of the major disorders under study. Clients can obtain full results and detailed recommendations in as little as 3-4 weeks.
Standard genotyping services are routinely performed at PsychoGenics with larger genotyping projects provided with the assistance of Laragen Inc. Back to Top |