Mania / Bipolar Disorder

                                                      Bipolar disorder is a psychiatric mood disorder, typically beginning in adolescence or early adulthood, which manifests itself variable periods of manic excitement, depressed lows, and normal mood. The following tests have predictive validity for drugs for the treatment of bipolar dsorder:

                                                      Amphetamine & CDP Induced Hyperactivity
                                                      This test has predictive validity for Mania and Bipolar disorder, and mimics the mania/psychosis associated with bipolar. ...more info
                                                      Prepulse Inhibition of Startle
                                                      The acoustic startle reflex is a very basic response to strong exteroceptive stimuli. It is widely used to assess sensorimotor reactivity in animals and humans ...more info