Overview

General Services
PsychoGenics supports development of the next generation of drugs to treat CNS disorders by providing a broad range of target screening, discovery and validation resources to pharmaceutical and biotech companies, academic institutions and not-for-profit research foundations. Business agreements range from consulting and designing drug discovery flow schemes with go/no-go decision steps, to fee-for-service testing, to onsite research training and management.

The company offers more than 40 validated in vivo behavioral tests, mostly in mice (some tests are also performed in rats). PsychoGenics is constantly updating its services by developing new behavioral models and approaches to behavioral testing. Services include:

  • Breeding
  • Genotyping
  • Behavioral Pharmacology
  • Phenotyping
  • Microdialysis
  • Radiotelemetry

Customized Services
PsychoGenics has established protocols and Standard Operating Procedures for the array of pharma-cologically validated tests it offers. However, the company is flexible and will modify protocols andestablish new tests to address client needs. Client work will not proceed until all tests pass PsychoGenics’ stringent validation requirements.

Clients
PsychoGenics has relationships with more than 60 pharmaceutical and biotech companies, and not-for-profit institutions, including Bristol-Myers Squibb, Eli Lilly, Janssen Pharmaceutica (the CNS division of Johnson & Johnson), F. Hoffmann-La Roche, Synaptic (now Lundbeck), the Salk Institute, Harvard Medical School/Massachusetts General Hospital, the ALS Association and the High Q Foundation. More than 85% of the company’s current business is repeat business.

Research Staff
The vast majority of PsychoGenics’ seventy-plus research staff have extensive pharmaceutical experience; sixteen have Ph.Ds. All research staff are highly trained in GLP standards and training records are available to our clients. Training is overseen by a GLP-trained Director of Quality Control and Safety. 

Among PsychoGenics’ areas of expertise is mouse behavior, including knowledge of the behavioral and neurological characteristics of the strains most commonly used to produce transgenic mice. Most of the tests in PsychoScreen™, PsychoGenics’ recommended battery of behavioral assays for phenotyping, have been studied in more than 10 strains of mice.

Facility
All work is conducted in an AAALAC compliant facility and supervised by a senior veterinarian. The highest standards of animal care are implemented to ensure that the facility is pathogen-free and that all animals are healthy. Two recent complete health reports must be provided for all animals entering the facility and a three-week quarantine is required for all non-vendor mice.


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