Novelty–Suppressed Feeding

Novelty-suppressed feeding (NSF) measures a rodent’s aversion to eating in a novel environment. This test assesses stress-induced anxiety by measuring the latency of an animal to approach and eat a familiar food in an aversive environment. The test is sensitive to acute administration of anxiolytics and chronic antidepressant treatment but insensitive to acute antidepressants. Novelty suppressed feeding is therefore one of the few behavioral tests differentially sensitive to chronic versus acute effects of antidepressants.

Novelty Suppressed Feeding

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