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Neurogenesis – In Vivo Neurogenesis – Screening

The relative efficiency and accuracy of the GC/MS method for measuring progenitor cell proliferation enables its use for screening novel compounds and evaluating dose-response relationships.

chart

Mice received chronic treatment with novel compounds for 3 weeks with 2H2O in the drinking water during the last 10 days of treatment. Several compounds significantly increased proliferation. * indicates p < .05, n = 6.

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Mice received chronic treatment with novel compounds for 3 weeks with 2H2O in the drinking water during the last 10 days of treatment. Several of the hits from the screening study exhibited dose-related responses. * indicates p < .05, n = 6.

 

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