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| Chemical-Induced Inflammatory Pain (Formalin, Carageenan) |
| Services - Pain - Chemical-Induced Inflammatory Pain (Formalin, Carageenan) |
| A sub-plantar administration of a chemical irritant such as formalin or carageenan measures nociception and inflammation in mice. These tests are useful in determining efficacy of steroidal and non-steroidal anti-inflammatory drugs and opiates. |
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A | B |
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| Morphine (5 mg/kg) has analgesic effects on a formalin-injected paw of C3H mice, as determined by descriptive behavioral observations (A) that provide an overall behavioral score (B). |
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| Pretreatment with naproxen (30 mg/kg) is seen to decrease carrageenan-induced mechanical hyperalgesia |
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